Background: To analyze the results of repeat selective laser trabeculoplasty (SLT).\nMethods: Inclusion criteria: participants with primary or secondary open-angle glaucoma (excluding uveitic) who\nhad undergone SLT 360Ã?° (SLT 1) with diminution of response over time followed by repeat SLT 360Ã?° (SLT 2). Six\nmonths of follow-up were required and at least 6 months in between SLT 1 and 2. The main outcome measures\nwere IOP reduction at 6 and 12 months and a comparison of the response between SLT 1 and 2.\nResults: One hundred thirty-seven patients met the inclusion criteria. If only one eye had repeat treatment, that eye\nwas chosen; if both eyes qualified, one was chosen at random. The baseline intraocular pressure (IOP) for SLT 1 = 20.3\n+/âË?â?? 5.2 mmHg and SLT 2 = 19.4 +/âË?â?? 5.0 was reduced to 16.4 +/âË?â?? 3.9 and 16.7 +/âË?â?? 4.7 at 1 year, respectively (p < .001).\nMedication use was not significantly changed, and was 2.2 +/âË?â?? 1.2 at baseline for SLT 1 and 2.1 +/âË?â?? 1.3 for SLT 2, and\nat 1 year was 1.9 +/âË?â?? 1.3 and 2.2 +/âË?â?? 1.2, respectively. A subanalysis of 62 patients matched for equivalent baselines\nshowed a baseline IOP = 18.7 +/âË?â?? 3.8 for SLT 1 and 18.7 +/âË?â?? 3.5 for SLT 2, reduced to 16.0 +/âË?â?? 4.3 and 15.3 +/âË?â?? 3.8 at\n1 year (p < .001).\nConclusion: Repeat SLT laser (360-degree treatment, followed by a loss of effect over time, then a second 360-degree\ntreatment) in this population resulted in IOP lowering similar to that of the initial treatment.
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